Severe pulmonary embolism decreases plasma L-arginine.
نویسندگان
چکیده
Comisión Honoraria de Lucha Antituberculosa y Enfermedades Prevalentes, Montevideo, Unidad de Biologı́a Molecular, Institut Pasteur de Montevideo, Montevideo, and Departamento de Bioquı́mica, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay. INSERM U1019-CNRS UMR 8204, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Univ Lille Nord de France, Lille, France.
منابع مشابه
Effects of oral supplementation of L-arginine in the treatment of pulmonary hypertension secondary to pulmonary embolism: a case report.
We tried L-arginine for the treatment of pulmonary hypertension secondary to pulmonary embolism. The plasma brain natriuretic peptide (BNP) level inversely correlated with the plasma concentration of L-arginine. After oral supplementation of L-arginine, patient's symptoms (shortness of breath and general malaise), state of congestive heart failure, and exercise capacity all improved. L-arginine...
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consumption in experimental and clinical acute pulmonary thromboembolism. Crit Care Med 2013; 41: e118–e124. 6 Levi M. Disseminated intravascular coagulation or extended intravascular coagulation in massive pulmonary embolism. J Thromb Haemost 2010; 8: 1475–1476. 7 Leitner JM, Jilma B, Spiel AO, et al. Massive pulmonary embolism leading to cardiac arrest is associated with consumptive coagulopa...
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Primary pulmonary hypertension (PPH) is a condition characterized by sustained elevation of pulmonary artery pressure (PAP) without demonstrable cause. The most common symptom at presentation is dyspnea. Other complaints include fatigue, chest pain, syncope, leg edema, and palpitations. Right heart catheterization is diagnostic, showing a mean PAP >25 mmHg at rest and >30 mmHg during exercise, ...
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The role of active thrombosis in the pathophysiology of pulmonary embolism is unclear. We tested the hypothesis that venous thrombi significantly increase their thrombotic activity once they embolize into the high-flow circulation of the pulmonary arteries. Thrombotic activity was measured using an immunoassay that measures both fibrinopeptide B (FPB) as well as its most abundant metabolite des...
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In this study, we investigated the possible interaction between the cationic amino acid transporter (CAT)-1 arginine transporter and ankyrin or fodrin. Because ankyrin and fodrin are substrates for calpain and because hypoxia increases calpain expression and activity in pulmonary artery endothelial cells (PAEC), we also studied the effect of hypoxia on ankyrin, fodrin, and CAT-1 contents in PAE...
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 43 3 شماره
صفحات -
تاریخ انتشار 2014